Amino Acid Properties (1)

Amino Acid			Molecular Formula	Hydropathy Index	log P	Acidic/Neutral/Basic	Polar/Hydrophobic	pI
Arg	R	Arginine	H2N(=NH)NHC3H6CCH(NH2)COOH	-4.5	-4.20	Acidic	Polar (Basic)	10.76
Lys	K	Lysine	H2N(CH2)4CH(NH2)COOH	-3.9	-3.05	Basic	Polar (Basic)	9.74
Asp	D	Aspartic Acid	HOOCCH2CH(NH2)COOH	-3.5	-3.89	Acidic	Polar (Acidic)	2.77
Asn	N	Asparagine	H2NCOCH2CH(NH2)COOH	-3.5	-3.82	Neutral	Polar (Neutral)	5.41
Glu	E	Glutamic Acid	HOOCCH2CH2CH(NH2)COOH	-3.5	-3.69	Acidic	Polar (Acidic)	3.22
Gln	Q	Glutamine	H2NCO-CH2CH2CH(NH2)COOH	-3.5	-3.64	Neutral	Polar (Neutral)	5.65
His	H	Histidine	H2NCH[CH2(C3H3N2)]COOH	-3.2	-3.32	Basic	Polar (Basic)	7.59
Pro	P	Proline	(C4H8N)-COOH	-1.6	-2.54	Neutral	Nonpolar (Hydrophobic)	6.30
Tyr	Y	Tyrosine	HO(C6H4)CH2CH(NH2)COOH	-1.3	-2.26	Neutral	Polar (Neutral)	5.66
Trp	W	Tryptophan	(C8H6N)-CH2CH(NH2)COOH	-0.9	-1.05	Neutral	Nonpolar (Hydrophobic)	5.89
Ser	S	Serine	HOCH2CH(NH2)COOH	-0.8	-3.07	Neutral	Polar (Neutral)	5.68
Thr	T	Threonine	CH3CH(OH)CH(NH2)COOH	-0.7	-2.94	Neutral	Polar (Neutral)	6.16
Gly	G	Glycine	H2NCH2COOH	-0.4	-3.21	Neutral	Nonpolar (Hydrophobic)	5.97
Ala	A	Alanine	CH3CH(NH2)COOH	1.8	-2.85	Neutral	Nonpolar (Hydrophobic)	6.00
Met	M	Methionine	CH3SCH2CH2CH(NH2)COOH	1.9	-1.87	Neutral	Nonpolar (Hydrophobic)	5.74
Cys	C	Cysteine	HSCH2CH(NH2)COOH	2.5	-2.49	Neutral	Polar (Neutral)	5.07
Phe	F	Phenylalanine	(C6H5)CH2CH(NH2)COOH	2.8	-1.38	Neutral	Nonpolar (Hydrophobic)	5.48
Leu	L	Leucine	(CH3)2CHCH2CH(NH2)COOH	3.8	-1.52	Neutral	Nonpolar (Hydrophobic)	5.98
Val	V	Valine	(CH3)2CHCH(NH2)COOH	4.2	-2.26	Neutral	Nonpolar (Hydrophobic)	5.96
Ile	I	Isoleucine	C2H5CH(CH3)CH(NH2)COOH	4.5	-1.70	Neutral	Nonpolar (Hydrophobic)	6.02

# hydropathy index; Kyte and Doolittle, J. Mol. Biol., 157, 105-132(1982)
# log P; On-Line Log P Calculation

Amino Acid Properties (2)

Amino Acid			hydropathy index	Side-chain R			log P	Acidic/Neutral/Basic	pI
				O	I	I/O *
Ile	I	Isoleucine	4.5	80	0	0	-1.70	Neutral	6.02
Leu	L	Leucine	3.8	70	0	0	-1.52	Neutral	5.98
Val	V	Valine	4.2	50	0	0	-2.26	Neutral	5.96
Ala	A	Alanine	1.8	20	0	0	-2.85	Neutral	6.00
Phe	F	Phenylalanine	2.8	140	15	0.107	-1.38	Neutral	5.48
Pro	P	Proline	-1.6	60	10	0.167	-2.54	Neutral	6.30
Met	M	Methionine	1.9	100	20	0.200	-1.87	Neutral	5.74
Cys	C	Cysteine	2.5	60	20	0.333	-2.49	Neutral	5.07
Trp	W	Tryptophan	-0.9	180	130	0.722	-1.05	Neutral	5.89
Tyr	Y	Tyrosine	-1.3	140	115	0.821	-2.26	Neutral	5.66
Lys	K	Lysine	-3.9	80	70	0.875	-3.05	Basic	9.74
Gly	G	Glycine	-0.4	0	0	-	-3.21	Neutral	5.97
His	H	Histidine	-3.2	80	152	1.900	-3.32	Basic	7.59
Arg	R	Arginine	-4.5	80	190	2.375	-4.20	Positive	10.76
Thr	T	Threonine	-0.7	40	100	2.500	-2.94	Neutral	6.16
Glu	E	Glutamic Acid	-3.5	60	150	2.500	-3.69	Acidic	3.22
Gln	Q	Glutamine	-3.5	60	200	3.333	-3.64	Neutral	5.65
Asp	D	Aspartic Acid	-3.5	40	150	3.750	-3.89	Acidic	2.77
Ser	S	Serine	-0.8	20	100	5.000	-3.07	Neutral	5.68
Asn	N	Asparagine	-3.5	40	200	5.000	-3.82	Neutral	5.41

* Formulation Design with Organic Conceptual Diagram - NIHON EMULSION CO., LTD [PDF]

Hemoglobin (PDB 2HHB) - Kawakami Model [Japanese]

Oct1/Sox2/DNA ternary complex (PDB 1GT0) - Kawakami Model [Japanese]

  
GPCR [Japanese]

    
The PFAS Problem [Japanese]

Booth 327 - Science Agora 2024

Conformational Preferences of the Amino Acids
Williams, R.W. et al. : Biochim. Biophys. Acta , 916, 200-204 (1987).
"From Sequence to Structure" [PDF], p.18

	α-helix	β-strand
Glu	1.59	0.52
Ala	1.41	0.72
Leu	1.34	1.22
Met	1.30	1.14
Gln	1.27	0.98
Lys	1.23	0.69
Arg	1.21	0.84
His	1.05	0.80
Val	0.90	1.87
Ile	1.09	1.67
Tyr	0.74	1.45
Cys	0.66	1.40
Trp	1.02	1.35
Phe	1.16	1.33
Thr	0.76	1.17
Gly	0.43	0.58
Asn	0.76	0.48
Pro	0.34	0.31
Ser	0.57	0.96
Asp	0.99	0.39

PDB 1C9E