〔左〕ニュース1の2w69A鎖,〔右〕ニュース2の3ebjA鎖
※Jmolで見るトピックス分子で構造参照可能
◆ニュース2
2W69と3EBJのアミノ酸配列の違い(FASTA Sequence,何れもA鎖について)
GMGSGMAMEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLE
LGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLE
※以下にこの配列について,1文字アミノ酸配列から各種HTMLデータを作成する秀丸マクロ により処理したデータを示す。
※赤字が最初の共通開始部分トップのMet
2W69:A|PDBID|CHAIN|SEQUENCE
VCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNS
ICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENT
HIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQ
SERGEETIEERFEITG
3EBJ:D|PDBID|CHAIN|SEQUENCE
VCFMYSDFHFIDERGESTIIESGDPNALLKHRFEIIEGRDRTMAWTVVNS
ICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHTYYLEKANKIKSEKH
IHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQS
ERGEETIEERFEITGTMCRLADQSLPPNFSSLEKFRAYVDGFEPNGCIEG
KLSQMSKEVNAR
2W69(アミノ酸別着色)
Gly | Met | Gly | Ser | Gly | Met | Ala | Met | Glu | Asp | Phe | Val | Arg | Gln | Cys | Phe | Asn | Pro | Met | Ile | Val | Glu | Leu | Ala | Glu | Lys | Ala | Met | Lys | Glu | Tyr | Gly | Glu | Asp | Leu | Lys | Ile | Glu | Thr | Asn | Lys | Phe | Ala | Ala | Ile | Cys | Thr | His | Leu | Glu |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Val | Cys | Phe | Met | Tyr | Ser | Asp | Phe | His | Phe | Ile | Asn | Glu | Gln | Gly | Glu | Ser | Ile | Val | Val | Glu | Leu | Asp | Asp | Pro | Asn | Ala | Leu | Leu | Lys | His | Arg | Phe | Glu | Ile | Ile | Glu | Gly | Arg | Asp | Arg | Thr | Met | Ala | Trp | Thr | Val | Val | Asn | Ser |
Ile | Cys | Asn | Thr | Thr | Gly | Ala | Glu | Lys | Pro | Lys | Phe | Leu | Pro | Asp | Leu | Tyr | Asp | Tyr | Lys | Glu | Asn | Arg | Phe | Ile | Glu | Ile | Gly | Val | Thr | Arg | Arg | Glu | Val | His | Ile | Tyr | Tyr | Leu | Glu | Lys | Ala | Asn | Lys | Ile | Lys | Ser | Glu | Asn | Thr |
His | Ile | His | Ile | Phe | Ser | Phe | Thr | Gly | Glu | Glu | Met | Ala | Thr | Lys | Ala | Asp | Tyr | Thr | Leu | Asp | Glu | Glu | Ser | Arg | Ala | Arg | Ile | Lys | Thr | Arg | Leu | Phe | Thr | Ile | Arg | Gln | Glu | Met | Ala | Asn | Arg | Gly | Leu | Trp | Asp | Ser | Phe | Arg | Gln |
Ser | Glu | Arg | Gly | Glu | Glu | Thr | Ile | Glu | Glu | Arg | Phe | Glu | Ile | Thr | Gly |
Leu | Gly | Ser | Met | Glu | Asp | Phe | Val | Arg | Gln | Cys | Phe | Asn | Pro | Met | Ile | Val | Glu | Leu | Ala | Glu | Lys | Ala | Met | Lys | Glu | Tyr | Gly | Glu | Asp | Pro | Lys | Ile | Glu | Thr | Asn | Lys | Phe | Ala | Ala | Ile | Cys | Thr | His | Leu | Glu | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Val | Cys | Phe | Met | Tyr | Ser | Asp | Phe | His | Phe | Ile | Asp | Glu | Arg | Gly | Glu | Ser | Thr | Ile | Ile | Glu | Ser | Gly | Asp | Pro | Asn | Ala | Leu | Leu | Lys | His | Arg | Phe | Glu | Ile | Ile | Glu | Gly | Arg | Asp | Arg | Thr | Met | Ala | Trp | Thr | Val | Val | Asn | Ser |
Ile | Cys | Asn | Thr | Thr | Gly | Val | Glu | Lys | Pro | Lys | Phe | Leu | Pro | Asp | Leu | Tyr | Asp | Tyr | Lys | Glu | Asn | Arg | Phe | Ile | Glu | Ile | Gly | Val | Thr | Arg | Arg | Glu | Val | His | Thr | Tyr | Tyr | Leu | Glu | Lys | Ala | Asn | Lys | Ile | Lys | Ser | Glu | Lys | His |
Ile | His | Ile | Phe | Ser | Phe | Thr | Gly | Glu | Glu | Met | Ala | Thr | Lys | Ala | Asp | Tyr | Thr | Leu | Asp | Glu | Glu | Ser | Arg | Ala | Arg | Ile | Lys | Thr | Arg | Leu | Phe | Thr | Ile | Arg | Gln | Glu | Met | Ala | Ser | Arg | Gly | Leu | Trp | Asp | Ser | Phe | Arg | Gln | Ser |
Glu | Arg | Gly | Glu | Glu | Thr | Ile | Glu | Glu | Arg | Phe | Glu | Ile | Thr | Gly | Thr | Met | Cys | Arg | Leu | Ala | Asp | Gln | Ser | Leu | Pro | Pro | Asn | Phe | Ser | Ser | Leu | Glu | Lys | Phe | Arg | Ala | Tyr | Val | Asp | Gly | Phe | Glu | Pro | Asn | Gly | Cys | Ile | Glu | Gly |
Lys | Leu | Ser | Gln | Met | Ser | Lys | Glu | Val | Asn | Ala | Arg |
Gly | Met | Gly | Ser | Gly | Met | Ala | Met | Glu | Asp | Phe | Val | Arg | Gln | Cys | Phe | Asn | Pro | Met | Ile | Val | Glu | Leu | Ala | Glu | Lys | Ala | Met | Lys | Glu | Tyr | Gly | Glu | Asp | Leu | Lys | Ile | Glu | Thr | Asn | Lys | Phe | Ala | Ala | Ile | Cys | Thr | His | Leu | Glu |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Val | Cys | Phe | Met | Tyr | Ser | Asp | Phe | His | Phe | Ile | Asn | Glu | Gln | Gly | Glu | Ser | Ile | Val | Val | Glu | Leu | Asp | Asp | Pro | Asn | Ala | Leu | Leu | Lys | His | Arg | Phe | Glu | Ile | Ile | Glu | Gly | Arg | Asp | Arg | Thr | Met | Ala | Trp | Thr | Val | Val | Asn | Ser |
Ile | Cys | Asn | Thr | Thr | Gly | Ala | Glu | Lys | Pro | Lys | Phe | Leu | Pro | Asp | Leu | Tyr | Asp | Tyr | Lys | Glu | Asn | Arg | Phe | Ile | Glu | Ile | Gly | Val | Thr | Arg | Arg | Glu | Val | His | Ile | Tyr | Tyr | Leu | Glu | Lys | Ala | Asn | Lys | Ile | Lys | Ser | Glu | Asn | Thr |
His | Ile | His | Ile | Phe | Ser | Phe | Thr | Gly | Glu | Glu | Met | Ala | Thr | Lys | Ala | Asp | Tyr | Thr | Leu | Asp | Glu | Glu | Ser | Arg | Ala | Arg | Ile | Lys | Thr | Arg | Leu | Phe | Thr | Ile | Arg | Gln | Glu | Met | Ala | Asn | Arg | Gly | Leu | Trp | Asp | Ser | Phe | Arg | Gln |
Ser | Glu | Arg | Gly | Glu | Glu | Thr | Ile | Glu | Glu | Arg | Phe | Glu | Ile | Thr | Gly |
Leu | Gly | Ser | Met | Glu | Asp | Phe | Val | Arg | Gln | Cys | Phe | Asn | Pro | Met | Ile | Val | Glu | Leu | Ala | Glu | Lys | Ala | Met | Lys | Glu | Tyr | Gly | Glu | Asp | Pro | Lys | Ile | Glu | Thr | Asn | Lys | Phe | Ala | Ala | Ile | Cys | Thr | His | Leu | Glu | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Val | Cys | Phe | Met | Tyr | Ser | Asp | Phe | His | Phe | Ile | Asp | Glu | Arg | Gly | Glu | Ser | Thr | Ile | Ile | Glu | Ser | Gly | Asp | Pro | Asn | Ala | Leu | Leu | Lys | His | Arg | Phe | Glu | Ile | Ile | Glu | Gly | Arg | Asp | Arg | Thr | Met | Ala | Trp | Thr | Val | Val | Asn | Ser |
Ile | Cys | Asn | Thr | Thr | Gly | Val | Glu | Lys | Pro | Lys | Phe | Leu | Pro | Asp | Leu | Tyr | Asp | Tyr | Lys | Glu | Asn | Arg | Phe | Ile | Glu | Ile | Gly | Val | Thr | Arg | Arg | Glu | Val | His | Thr | Tyr | Tyr | Leu | Glu | Lys | Ala | Asn | Lys | Ile | Lys | Ser | Glu | Lys | His |
Ile | His | Ile | Phe | Ser | Phe | Thr | Gly | Glu | Glu | Met | Ala | Thr | Lys | Ala | Asp | Tyr | Thr | Leu | Asp | Glu | Glu | Ser | Arg | Ala | Arg | Ile | Lys | Thr | Arg | Leu | Phe | Thr | Ile | Arg | Gln | Glu | Met | Ala | Ser | Arg | Gly | Leu | Trp | Asp | Ser | Phe | Arg | Gln | Ser |
Glu | Arg | Gly | Glu | Glu | Thr | Ile | Glu | Glu | Arg | Phe | Glu | Ile | Thr | Gly | Thr | Met | Cys | Arg | Leu | Ala | Asp | Gln | Ser | Leu | Pro | Pro | Asn | Phe | Ser | Ser | Leu | Glu | Lys | Phe | Arg | Ala | Tyr | Val | Asp | Gly | Phe | Glu | Pro | Asn | Gly | Cys | Ile | Glu | Gly |
Lys | Leu | Ser | Gln | Met | Ser | Lys | Glu | Val | Asn | Ala | Arg |