Ÿ Œõ‡Ž Œõ‰ŧŠwŒnII‚Ė•”•Š\‘Ē—áig˜c‚ņ‚ūˆÖŽqhj Ÿ
s ‹Œƒ^ƒCƒgƒ‹F Œõ‡Ž‚ÉŠÖŒW‚·‚éķ‘Ė•ŠŽqPDB 3ARC‚Ė•”•Š\‘Ē—á t
Ļ Œõ‡Ž‚ÉŠÖŒW‚·‚éķ‘Ė•ŠŽq‚ĖSITE—á Đ
Ķ2014/09/03‚É3ARC‚ĖXVƒf[ƒ^3WU2‚ŠŒöŠJ‚ģ‚ę‚Ü‚ĩ‚―B

[TOPIC] 2014/12/03‚ÉSACLA‚É‚æ‚éƒtƒFƒ€ƒg•bXüŒ‹ŧ\‘Ē‰ðÍ–@‚ʼnðÍ‚ģ‚ę‚č\‘Ē‚ŠŒöŠJ‚ģ‚ę‚Ü‚ĩ‚―B Ļ JmolƒgƒsƒbƒNƒX
[TOPIC] ‘åãŽs—§‘åŠw‚ƉŠŽR‘åŠw‚Ėƒ`[ƒ€‚É‚æ‚éŒĪ‹†‚ŠScienceŽ‚ĖBreakthrough of the Year, 2011‚É‘I‚΂ę‚Ü‚ĩ‚―B

      

ƒAƒ~ƒmŽ_‚Ļ‚æ‚Ņ“ÁŦŠî‚Ėe…ŦE‘a…Ŧ b Log P‚ðƒ|ƒPƒbƒg‚ɁI


mŽQln Î–k ‰›CwXüŒ‹ŧ\‘Ē‰ðÍ‚É‚æ‚éŒõ‡Ž”―‰ž‹@\‚Ė—‰ðxCu‰ŧŠwv2017”N12ŒŽ†Cp.64 }1ip.65‚Å5ws5‚ĖMn4CaO6ƒNƒ‰ƒXƒ^[‚É‚āŒū‹yj



ƒoƒbƒNƒ{[ƒ“@“ņŽŸ\‘Ē
‘S‘I‘ð@ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@ƒŠƒKƒ“ƒh‘I‘ð
Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð@ƒNƒƒƒtƒBƒ‹aiCLAj‘I‘ð@ƒĀƒJƒƒeƒ“iBCRj‘I‘ð
iˆę•û‚ĖMn4CaO5ƒNƒ‰ƒXƒ^[‚Ė‹ß–T4•ŠŽq‚Ė‚݁j

‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒNi‘ūj@j‹ā@Á‹Ž
ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

Ž_ŦE’†ŦE‰–ŠîŦ‹æ•Ę@‹ÉŦE”ņ‹ÉŦ‹æ•Ę
‘a…ŦƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“ÁŦŠî Rj@“™“d“_‡
ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘ðŦiƒŋƒwƒŠƒbƒNƒXEƒĀƒXƒgƒ‰ƒ“ƒhj
…‘fŒ‹‡i‘ūj@OFF
@
@@
”wŒiE•@ŠD@”’@Ū
3arc‚ĖChain AiThermosynechococcus vulcanus‚ĖŒõ‰ŧŠwŒnIIGŒŧÝ3arc‚Í3wu2‚ɍXVj@“ŊPDBsumƒf[ƒ^ 3arc_OEXiMn4CaO5ƒNƒ‰ƒXƒ^[G…4•ŠŽq’Į‰Áj*$
Œõ‰ŧŠwŒnII‚Ė‘S‘Ė\‘Ē—áF 5tis@Chain AiMn4CaO5ƒNƒ‰ƒXƒ^[ŠÜ‚ށj‘I‘ð@Chain MiPsbMƒNƒ‰ƒXƒ^[j‘I‘ð@PL9iƒvƒ‰ƒXƒgƒLƒmƒ“-9j‘I‘ð
yˆČ‰šŽQlz
  • SACLA‚É‚æ‚é2014/12/03ŒöŠJƒf[ƒ^F4ub6‚ĖChain Ai“Ŋãj@PL9‘I‘ð
  • 2016/01/20ŒöŠJƒf[ƒ^F4yuu‚ĖChain AicifƒtƒH[ƒ}ƒbƒgj
  • 2016/05/25ŒöŠJƒf[ƒ^F3jcu‚ĖChain A-Z@PL9‘I‘ð
  • 2016/11/23ŒöŠJƒf[ƒ^F5kaf‚ĖChain A b 5kai‚ĖChain A b 5tis‚ĖChain A@PL9‘I‘ð
  • 2017/02/01ŒöŠJƒf[ƒ^F5b5e‚ĖChain A b 5b66‚ĖChain A@PL9‘I‘ð
  • 2017/03/15ŒöŠJƒf[ƒ^F5gth‚ĖChain A b 5gti‚ĖChain A b 5ws5‚ĖChain A b 5ws6‚ĖChain A@OEYiMn4CaO6ƒNƒ‰ƒXƒ^[j‘I‘ð@PL9‘I‘ð a ĶŽQlF 5ws5‚ĖChain MiPsbMj b 5ws6‚ĖChain M
  • 2017/03/22ŒöŠJƒf[ƒ^F5h2fiPsbMŒ‡‘đj‚ĖChain A@PL9‘I‘ð@“ŊPDBsumƒf[ƒ^5h2f_OEX$
  • 2017/08/30ŒöŠJƒf[ƒ^F5v2c‚ĖChain A@PL9‘I‘ð@“ŊPDBsumƒf[ƒ^5v2c_OEX$
  • 2017/09/20ŒöŠJƒf[ƒ^F5xnl‚ĖChain AiƒNƒ‰ƒCƒI“dŽqŒ°”ũ‹ū‚É‚æ‚éj@PL9‘I‘ð@“ŊPDBsumƒf[ƒ^5xnl_OEX$@Ļ JmolƒgƒsƒbƒN
  • 2018/08/01ŒöŠJƒf[ƒ^F5zzn‚ĖChain A@PL9‘I‘ð@“ŊPDBsumƒf[ƒ^5zzn_OEX$
  • 2018/11/21ŒöŠJƒf[ƒ^F6dho‚ĖChain A@PL9‘I‘ð@OEYiCa-Mn4-O6 clusterj‘I‘ð@“ŊPDBsumƒf[ƒ^5zzn_OEX$
  • 2019/07/31ŒöŠJƒf[ƒ^F6jlu‚ĖChain A [NEW!]@PL9‘I‘ð@PHOiƒtƒFƒIƒtƒBƒ`ƒ“aj‘I‘ð
  • 2019/07/31ŒöŠJƒf[ƒ^F6j40‚ĖChain C [NEW!]
  • 2019/10/16ŒöŠJƒf[ƒ^F6jlpm3F state, dataset2n‚ĖChain A [NEW!]@OEX‘I‘ð@OEY‘I‘ð@“ŊOEXEOEY‚Ėd‚ˍ‡‚í‚đ\‘Ē‚Ė‚݁@“ŊPDBsumƒf[ƒ^6jlp_OEX$@“ŊPDBsumƒf[ƒ^6jlp_OEY$ b 6jlom2F state, dataset2n‚ĖOEXEOEYd‚ˍ‡‚í‚đ\‘Ē‚Ė‚݁@“ŊPDBsumƒf[ƒ^6jlo_OEX$@“ŊPDBsumƒf[ƒ^6jlo_OEY$ b 6jlnm1F state, dataset2n‚ĖOEXEOEYd‚ˍ‡‚í‚đ\‘Ē‚Ė‚݁@“ŊPDBsumƒf[ƒ^6jln_OEX$@“ŊPDBsumƒf[ƒ^6jln_OEY$
  • 2019/10/23ŒöŠJƒf[ƒ^F6kad‚ĖChain A [NEW!]
  • Œõ‡ŽŒõ‰ŧŠwŒnII‚Ė\‘Ē—á3arc‚ĖChain A ‚Ų‚Đ
    ĶƒŠƒKƒ“ƒh‚ÍOEXiMn4CaO5ƒNƒ‰ƒXƒ^[G‹ß–T‚ɐ…4•ŠŽqjCCLAiƒNƒƒƒtƒBƒ‹ajCPHOiƒtƒFƒIƒtƒBƒ`ƒ“aj‚Ė‚Ý
    ĶŽQlF
    Œõ‡ŽŽ_‘f”­ķ‚Ė“ä‚ð‰ð–ūiSPring-8C2011/04/18j Ļ ŠÖ˜A“Ū‰æŽQÆ

      
    PyMOL‚É‚æ‚éã‹Lƒ‚ƒfƒ‹•\ŽĶ—áiķj‚ÆKawakami Modeli‰Ej

      
    PyMOL‚É‚æ‚éã‹Lƒ‚ƒfƒ‹•\ŽĶ—áiķj‚ÆKawakami Modeli‰Ej

      
    PDB 5tisiChain AEM‚ð‹…•\ŽĶGķj‚Æ5ws6‚ĖChain MiPsbMƒTƒuƒ†ƒjƒbƒgG‰Ej



    ƒoƒbƒNƒ{[ƒ“@“ņŽŸ\‘Ē
    ‘S‘I‘ð@ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@ƒŠƒKƒ“ƒh‘I‘ð
    Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð
    iˆę•û‚ĖMn4CaO5ƒNƒ‰ƒXƒ^[‚Ė‹ß–T4•ŠŽq‚Ė‚݁j

    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒNi‘ūj@j‹ā
    ƒAƒ~ƒmF@ChainF@CPKF@a@JmolF@RasmolF

    Ž_ŦE’†ŦE‰–ŠîŦ‹æ•Ę@‹ÉŦE”ņ‹ÉŦ‹æ•Ę
    ‘a…ŦƒCƒ“ƒfƒbƒNƒX‡@I/O’l‡i“ÁŦŠî Rj@“™“d“_‡
    ƒRƒ“ƒzƒ[ƒVƒ‡ƒ“‘I‘ðŦiƒŋƒwƒŠƒbƒNƒXEƒĀƒXƒgƒ‰ƒ“ƒhj
    …‘fŒ‹‡i‘ūj@OFF
    @
    @@
    ”wŒiE•@ŠD@”’@Ū
    “Ŋã
    ĶƒŠƒKƒ“ƒh‚ÍOEX‚Ė‚݁i‹ß–T‚ɐ…4•ŠŽqj




    3arc_OEXiMn4CaO5ƒNƒ‰ƒXƒ^[G…4•ŠŽq’Į‰Áj
    I'/O'2.1825
    ƒŠƒKƒ“ƒh‹…–_•\ŽĶ
    ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð@…•ŠŽq‘I‘ð
    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ā@Á‹Ž
    CPKF@Ž_ŦE’†ŦE‰–ŠîŦ@I/O’l‡

    ”wŒiE•@ŠD@”’@Ū

    3wu2_OEXiMn4CaO5ƒNƒ‰ƒXƒ^[G3arc‚ĖXVƒf[ƒ^j
    I'/O'2.1825
    ƒŠƒKƒ“ƒh‹…–_•\ŽĶ
    ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð
    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ā@Á‹Ž
    CPKF@Ž_ŦE’†ŦE‰–ŠîŦ@I/O’l‡

    ”wŒiE•@ŠD@”’@Ū

    3jcu_OEXiMn4CaO5ƒNƒ‰ƒXƒ^[j
    I'/O'2.3923
    ƒŠƒKƒ“ƒh‹…–_•\ŽĶ
    ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð
    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ā@Á‹Ž
    CPKF@Ž_ŦE’†ŦE‰–ŠîŦ@I/O’l‡

    ”wŒiE•@ŠD@”’@Ū
    ĶMn4CaO5ƒNƒ‰ƒXƒ^[‚ðŠÜ‚Þ2014/07/08ŒöŠJƒf[ƒ^ŒfÚJmolƒgƒsƒbƒNƒXC‚Ļ‚æ‚Ņ2014/07/15ŒöŠJƒf[ƒ^ŒfÚƒgƒsƒbƒNƒXiNature ƒnƒCƒ‰ƒCƒgC2014/09/11jŽQÆ


    5kaf_OEXiMn4CaO5ƒNƒ‰ƒXƒ^[j[Chain A]
    dark-adapted (S1)
    I'/O'2.3923
    ƒŠƒKƒ“ƒh‹…–_•\ŽĶ
    ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð
    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ā@Á‹Ž
    CPKF@Ž_ŦE’†ŦE‰–ŠîŦ@I/O’l‡

    ”wŒiE•@ŠD@”’@Ū

    5kai_OEXiMn4CaO5ƒNƒ‰ƒXƒ^[j[Chain A]
    ammonia-bound two-flash illuminated (2F-NH3; S3-enriched)
    I'/O'2.1825
    ƒŠƒKƒ“ƒh‹…–_•\ŽĶ
    ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð
    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ā@Á‹Ž
    CPKF@Ž_ŦE’†ŦE‰–ŠîŦ@I/O’l‡

    ”wŒiE•@ŠD@”’@Ū

    5tis_OEXiMn4CaO5ƒNƒ‰ƒXƒ^[j[Chain A]
    two-flash illuminated (2F; S3-enriched)
    I'/O'2.3923
    ƒŠƒKƒ“ƒh‹…–_•\ŽĶ
    ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð
    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ā@Á‹Ž
    CPKF@Ž_ŦE’†ŦE‰–ŠîŦ@I/O’l‡

    ”wŒiE•@ŠD@”’@Ū
    Ķ2016/11/23ŒöŠJ‚ĖMn4CaO5ƒNƒ‰ƒXƒ^[‚ĖPDBsumƒf[ƒ^iNatureC2016/11/21jŽQÆ


    5ws5_OEXiMn4CaO5ƒNƒ‰ƒXƒ^[j[Chain A]
    dark-adapted (S1)
    I'/O'2.3923
    ƒŠƒKƒ“ƒh‹…–_•\ŽĶ
    ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð
    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ā@Á‹Ž
    CPKF@Ž_ŦE’†ŦE‰–ŠîŦ@I/O’l‡

    ”wŒiE•@ŠD@”’@Ū

    5ws6_OEXiMn4CaO5ƒNƒ‰ƒXƒ^[j[Chain A]
    ammonia-bound two-flash illuminated (2F-NH3; S3-enriched)
    I'/O'2.3923
    ƒŠƒKƒ“ƒh‹…–_•\ŽĶ
    ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@Mn4CaO5ƒNƒ‰ƒXƒ^[‘I‘ð
    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ā@Á‹Ž
    CPKF@Ž_ŦE’†ŦE‰–ŠîŦ@I/O’l‡

    ”wŒiE•@ŠD@”’@Ū

    5ws6_OEYiMn4CaO6ƒNƒ‰ƒXƒ^[j[Chain A]
    two-flash illuminated (2F; S3-enriched)
    I'/O'2.1825
    ƒŠƒKƒ“ƒh‹…–_•\ŽĶ
    ƒ^ƒ“ƒpƒNŽŋ‘I‘ð@Mn4CaO6ƒNƒ‰ƒXƒ^[‘I‘ð
    ‹óŠÔ[“U@‹…–_@‹…60“@ƒXƒeƒBƒbƒN@j‹ā@Á‹Ž
    CPKF@Ž_ŦE’†ŦE‰–ŠîŦ@I/O’l‡

    ”wŒiE•@ŠD@”’@Ū
    Ķ2017/03/15ŒöŠJ‚ĖMn4CaO5ƒNƒ‰ƒXƒ^[‚Ļ‚æ‚ŅMn4CaO6ƒNƒ‰ƒXƒ^[‚ĖPDBsumƒf[ƒ^iSPring-8C2017/02/21jŽQÆ



    3arc‘S‘Ė\‘Ē


    3arc‚ĖChain Aiķ‚̓ŠƒKƒ“ƒh‚Æ‚ĩ‚ÄOEXECLAEPHO‚ðŠÜ‚݁C‰E‚ÍOEX‚Ė‚݁j

      
    g˜c‚ņ‚ūˆÖŽqh‚ ‚é‚Ē‚́g‚ä‚Š‚ņ‚ūˆÖŽqh‚Æ•\Œŧ‚ģ‚ę‚éƒNƒ‰ƒXƒ^[


    g˜c‚ņ‚ūˆÖŽqh



    uķŠˆŠÂ‹Ŧ‰ŧŠw‚Ė•”‰Ūvƒz[ƒ€ƒy[ƒW b Jmol”Łu•ŠŽq‚ĖŠwK’ v b Chime”Łu•ŠŽq‚ĖŠwK’ v